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This Concept Map, created with IHMC CmapTools, has information related to: hershel greene 2024, Disseminated Intravascular Coagulation Increase in tissue factor along with high D-Dimers is common in Disseminated Intravascular Coagulation D-dimer test, aspirin Inhibits platelet function by inhibiting COX1 & therefore decreasing PLT platelets, hematocrit Hematocrit measures the proportion of blood that are RBCs, which contain hemoglobin. hemoglobin, plasminogen plasminogen is converted to plasmin by tissue plasminogen activators, to start breaking down the clot at site of injury plasmin, Disseminated Intravascular Coagulation Prolonged due to intravascular thrombi partial thromboplastin time (pTT), Hershel Green Chief Complaint: "Suddenly had this pain in my chest, especially when I breathe in", igG IgG antibodies against COMPLEX of heparin bound to PF4, causing HIT PF4, Disseminated Intravascular Coagulation Increase in tissue factor along with high D-Dimers is common in Disseminated Intravascular Coagulation tissue factor, Diagnostic Labs pt score was a 7, showing a high probability of HIT 4T score, vitamin K factor 7 is inhibited by warfarin factor VII, "Suddenly had this pain in my chest, especially when I breathe in" as part of a comprehensive workup for CC of chest pain, labs were performed Diagnostic Labs, plasmin plasmin cleaves fibrin & serum fibrinogen, blocks platelet aggregation & destroys coagulation factors fibrinogen (factor I), fibrinogen (factor I) fibrinogen gets converted to fibrin to further form the clot fibrin, CBC CBC results for pt show a below normal range hematocrit hematocrit, von willebrand factor vWF binds to exposed collagen in vascular injury vascular injury, OSE pt has acute TART changes over thoracic & cervical region, commonly seen in acute pulmonary embolisms due to the T3-5 sympathetics + vagus nerve effecting pulmonary vasculature pulmonary embolism, vitamin K warfarin is a Vit K inhibitor and can be inactivated by Vit K warfarin, Diagnostic Labs results were positive, heparin binds to PF4, to inavtivate PF4 ELISA, endothelium TNF is a mediator of endothelial injury (implicated in DIC occurring with sepsis); induces endothelial cells to express tissue factor & decreases expression of thrombomodulin, tilts balance towards coagulation tissue factor, igG IgG antibodies detected in this assay. serotonin release assay