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This Concept Map, created with IHMC CmapTools, has information related to: robert dillon 2024, Bradykinin Bradykinin are released by mast cells, which contribute to the inflammation of this Vasculitis, Robert Dillon 28yo Hispanic Male Chief Complaint "I have a rash that is spreading everywhere", Sulfonamides Sulfa drug allergy can cause the adverse effect of SJS Steven Johnson Syndrome, IgG Mediates systemic (serum sickness) reactions through exogenous, non-human Abs/drug induced such as.. Antivenom, Type II hypersensitivity Adaptive immune response Type III hypersensitivity, TCR These receptors can be found on these cells, which trigger an immune response T-cytotoxic cells, Type III hypersensitivity Antigen-antibody aggregates activate immune cytokines IgG, Antibody-mediated Antibody used in type II hypersensitvity reaction resulting in cell damage IgG, Type IV hypersensitivity SJS- type IV hypersensitivity reaction involving toxic epidermal necrolysis of 10% of the skin & mucous membranes Steven Johnson Syndrome, Immunosuppressants Modify gene transcription to reduce inflammation and prevent rejection Corticosteroids, Immunosuppressants Immunosuppressants goal is to suppress foreign MHC molecules presented by the transplanted organ to prevent rejection. MHC Molecules, Vasculitis GC used to prevent liver rejection, if fail. If liver is infected with HepC while immunosupressed, can cause vascsulitis Corticosteroids, Myasthenia Gravis MG- type II hypersensitivity reaction against the body's Ach receptors Antibody-mediated, TCR These receptors can be found on these cells, which trigger an immune response T-helper cells, Type IV hypersensitivity Intradermal injection of antigen can be used as a tuberuclin test PPD, Fever Pt admits to having a fever prior to the rash Robert Dillon 28yo Hispanic Male, "I have a rash that is spreading everywhere" Dermatitis is a common symptom of type iv hypersensitivity reactions Type IV hypersensitivity, PPD Only Cell mediated immune reactiosn will test positive in TB skin testing Cell-mediated, Type I hypersensitivity Adaptive immune response Type II hypersensitivity, Type III hypersensitivity Adaptive immune response Type IV hypersensitivity