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This Concept Map, created with IHMC CmapTools, has information related to: Untitled, serotonin Serotonin regulates the release of glutamate and GABA GABA, Olanzapine Both drugs used to treat sx of schizophrenia Haloperidol, Jack Dawson, 25 yo male family hx pertinent + for bipolar disorder, mom 52, alive Bipolar disorder, Negative symptoms a negative symptom showing reduced motivation Apathy, 5-HT2a receptor Block of 5-HT2a receptor in tuberoinfundibular pathway decreases release of prolactin tuberoinfundibular pathway, serotonin Serotonin regulates the release of glutamate and GABA Glutamate, nigrostriatal pathway Degeneration in this pathway leads to Parkinsonism, a symptom complex including tremor & rigidity Parkinsonism, Bipolar disorder Presents with manic & possibly hypomanic episodes. Bipolar I, Haloperidol Typical antipsych drugs can cause hyperprolactinemia tuberoinfundibular pathway, mesocortical pathway low dopamine in the mesocortical pathway leads to negative symptoms Negative symptoms, Extrapyramidal symptoms EPS often mimic symptoms of Parkinson’s disease, such as tremors, rigidity, & bradykinesia. Parkinsonism, thyroid stimulating hormone Low TSH levels indicate hyperthyroidism Hyperthyroidism, G protien coupled receptor Many GPCRs are dopamine receptors, which play critical roles in neurotransmission & brain function. dopamine, Jack Dawson, 25 yo male got diagnostic labs in ER to aid differential Urine drug screen, dopamine Pathway involves dopamine neurotransmission impacting cognition and emotion. mesocortical pathway, Positive symptoms positive symptom consisting of false beliefs on an inaccurate perception of reality ????, MME score of 23 a score of 23 or less, indicates cognitive impairment which is indicatative of a psychotic episode Psychotic episode, D2 receptor Primarily by blocking D2 receptors, reducing psychotic symptoms. Haloperidol, NMDA receptor NMDA receptor is a type of glutamate receptor Glutamate, Jack Dawson, 25 yo male got diagnostic labs in ER to aid differential thyroid stimulating hormone