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This Concept Map, created with IHMC CmapTools, has information related to: Untitled, Hershel Greene 65 year old male Presents to ED with SOB and acute sharp chest pain Diagnostic exams to differentiate cause, Aspirin Patient's take as a prophylaxis for platelt coagulation, which can lead to thrombosis Platelets, LMWH can lead to adverse effects including Anemia, TPA creates breakdown product from plasminogen Plasmin, Warfarin competitively inhibits the production of Vitamin K, Hershel Greene 65 year old male Positive test PF4, 4T score is used as a diagnostic test to evaluate likelyhood of HIT Heparin induced thrombocytopenia, Endothelium secretes vWF to initiate formation of the platelet plug in primary hemostasis von Willebrand factor, Aspirin can prevent vascular injury vascular injury, Plasminogen is activated by TPA, von Willebrand factor bind to subendothelial collagen, linking it to Gp1b/1x Platelets, IgG IgG binds to Fc portion of platelts, creating thrombosis Thrombosis, Heparin Enhances ATIII, leading to increased inhibition of factors IIa and Xa, as well as VII, IX, XI, XII Antithrombin (AT), Hematocrit meausres amount of RBCs Diagnostic exams to differentiate cause, TPA Drug given to destroy clots causing pathological damage Myocardial infarction, Thrombin negative feedback and anticoagutlatin mediated by activating Antithrombin (AT), Extrinsic pathway Activated by trauma that causes blood to leave vasculature Tissue factor, EKG is used as a diagnostic tool for detection of cardiac events such as Myocardial infarction, Partial thromboplastin time (PTT) evaluates the effectiveness of the intrinsic pathway Intrinsic pathway, Plasminogen inactive form converted to active plasmin Plasmin