WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: Jack_Dawson_C3_Final, Mesolimbic pathway D2 receptor blockade is the main mechanism typical antipsychotics for treatment of positive symptoms of schizophrenia D2 Receptor, PCP is an antagonist, which disinhibits dopamine, and intoxication can lead to violence and nystagmus NMDA Receptor, Aggression there is a correlation between low TSH levels (hypothyroidism) and an increase in aggression Thyroid Stimulating Hormone (TSH), G protein-coupled receptor (GPCR) is a GPCR in the serotonin receptor family Serotonin, DSM (Diagnostic and statistical manual) according to the DSM, bipolar I disorder involves manic episodes lasting one week at a time and depressive symptoms for at least 2 weeks, while bipolar II disorder involves at least on hypomanic and depressive episode Bipolar disorder, Diagnostic Findings: TSH - normal Urine Drug Screen - (+)PCP Neck - no tenderness, palpable masses, thyroid not palpable, trachea is midline because TSH findings and neck palpation are normal, psychosis is not as likely to be due to thyroid under- or overactivity Hypothyroidism, Hypothyroidism may be a cause of increased Aggression, Thyroid Stimulating Hormone (TSH) it is recommended that labs for TSH are ordered if schizophrenia is suspected because TSH levels may be increased in chronic schizophrenia and decreased in acute schizophrenia Schizophrenia, Diagnostic Findings: TSH - normal Urine Drug Screen - (+)PCP Neck - no tenderness, palpable masses, thyroid not palpable, trachea is midline Positive drug screen for PCP Urine Drug Screen, Myxedema is a condition that induces swelling and waxy skin overlying the thyroid due to underactive glands and can also induce psychosis Hypothyroidism, Haloperidol very potent first generation antipsychotic which can cause side effecs such as Tardive Dyskinesia through over antagonism of the D2 receptor Extrapyramidal symptoms (EPS), Glutamate NMDA receptors can be mutated in patients with schizophrenia leading to faulty memory formation Schizophrenia, Serotonin Serotonin inhibits dopamine release in the nigrostriatal pathway Nigrostriatal pathway, Jack Dawson presents with Delusions, D2 Receptor blocking D2 receptors in the tuberoinfundibular area results in increase prolactin release which causes milk lactation and infertility in females and gynecomastia in males Tuberoinfundibular pathway, Bipolar disorder schizophrenia is a differential diagnosis for the mania experienced in bipolar disorders Schizophrenia, Alcohol alcohol can be detected using a urinalysis up to 24 hours after ingesiont Urine Drug Screen, Schizophrenia according to the DSM, a diagnosis of schizophrenia requires 6 months of illness and at least 1 month of acute symptoms, 2 of which must be psychotic symptoms DSM (Diagnostic and statistical manual), Thyroid Stimulating Hormone (TSH) TSH levels ɰ.5 mlU/L support a diagnosis of hypothyroidism Hypothyroidism, Negative Symptoms such as apathy, social isolation, and poor speech is usually treated using atypical antipsychotics that target the Mesocortical pathway