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This Concept Map, created with IHMC CmapTools, has information related to: GROUP 2 CONCEPT MAP DRAFT 6PM, NECROTIZING ULCERATIVE GINGIVITIS includes systemic antimicrobial therapy, changes in gingival architecture following NUG particularly interdental cratering, VIRULENT PATHOGEN to progress to PERIODONTITIS, INF-y which causes formation of osteoclasts, host cells including epithelial cells, Inflammatory infiltrates comprised of mostly plasma cells, CLINICAL FEATURES include Knife-edge Margins, chemical mediators specifically high levels of TNF-a, Dark red or magenta in color due to Prevention of circulation w/ increased interstitial pressure, INF-y which causes bone resorption, GINGIVITIS ???? MICROBIAL COMPOSITION, Established lesion involving Apical epithelium migration, adhesin receptors that can be either Afimbrial, Acute Inflammatory Response manifests as EARLY LESION, mainstay of the treatment but if gingival destruction is severe, mostly are lymphocytes, formation of GCF causing extracellular spaces at junctional epithelium to widen, Chemoattractants will induce leukocyte extravasation, Gingivitis associated with an increased percentage of gram negative organisms (15-50%), MOLECULAR ADSORPTION/ PELLICLE FORMATION proceeds to BACTERIAL ADHESION BY SINGLE MICROORGANISM