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Deze Concept Map heeft informatie gerelateerd aan: 2B TGF beta, co-Smad (Smad4) bindt co-Smad + R-Smad complex, 17p13.1 bevat P53, MDM2 codeert Mdm2, CDKN2A codeert p16, 18q21.1 bevat SMAD2, Mdm2 ubiquitinates p53, co-Smad + R-Smad complex activeert P15/CDKN2B, TGFβ behoort tot TGFβ superfamily, P15/CDKN2B codeert p15, R-Smad (Smad1/2/3/5/8) bindt co-Smad + R-Smad complex, BMP behoort tot TGFβ superfamily, SMAD6/7 codeert I-Smad (Smad6/7), Activin behoort tot TGFβ superfamily, co-Smad + R-Smad complex activeert P21/CDKN1A, 9p21.3 bevat CDKN2A, p53 induceert MDM2, SMAD2 codeert R-Smad (Smad1/2/3/5/8), DCC codeert DCC, Type 1 receptor fosforyleert R-Smad (Smad1/2/3/5/8), SMAD4 codeert co-Smad (Smad4)