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This Concept Map, created with IHMC CmapTools, has information related to: Epilepsy Paper- Sophie, Materials and Methods recordings read through electrocorticographic recordings, Nav 1.1 Protein expression in homozygous knock-in mice had Premature Death, Results pups born with mutation Developed reoccuring seizures, Immunohistochemistry and immunoflouresence histochemisty revealed heterozygous fast-spiking interneurons that should be regarded as PV interneurons, Materials and Methods generation of SCN1A Gene, Results three differnet antibodies in the hetero distribution shows Nav1.1 expression in the caudal brain is higher than that in the rostral brain, Spontaneous Seizures could lead to Premature Death, Blot analysis ???? Northern, Immunohistochemistry and immunoflouresence histochemisty originally showed that Nav1.1 is generally localized to somata and dendrites of neurons, Current Clamp Analysis as seen in Figure 2, Immunohistochemistry and immunoflouresence histochemisty showed Nav 1.1 is homogenously distributed in the brain, Results developed in mouse brains Hetero Regional distribution of Scn1a mRNA and Nav1.1 protein, Knock in mutation in SCN1A Gene, Northern studies RNA, Nav 1.1 mutation leads to haploinsuffficiency, electrodes in Cerebellum, Results mutation lead to Spontaneous Seizures, Spike output of segments of PV interneurons, Blot analysis ???? Southern, Results figure 6 showed Nav 1.1