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Deze Concept Map heeft informatie gerelateerd aan: werkgroep 2B, cyclinD+CDK4/6 ???? celcyclus progressie, DNA-schade activeert p53 gen, p53 gen activeert p53, cyclinE+CDK2 ???? celcyclus progressie, p15 remt cyclinD+CDK4/6, Cofactor+SMD4+SMAD2/3 (in celkern) transcriptie van p21 gen, Cofactor+SMD4+SMAD2/3 (in celkern) transcriptie van p15 gen, p53 ???? apoptose, p15 gen activeert p15, p21 gen activeert P21, TGF beta ligand + TGF beta type 2 receptor + SMAD eiwit fosforylatie van serine Cofactor+SMD4+SMAD2/3 (in celkern), P21 remt cyclinE+CDK2, p53 activeert p21 gen