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This Concept Map, created with IHMC CmapTools, has information related to: Bacteriology 6 gram positive bacilli anaerobes, Gm+ bacilli non-spore forming Propionibacterium skin (acne), C. tetani char terminal spores club appearance, C. botulinum Dx detection in food serum, feces, C. botulinum char serotypes ABEF are pathogenic in humans food poisoning, C. difficile Tx discontinue offending AB might have to resort to oral metronidazole vancomycin metro-van runs through GI not absbd into bloodstrm, Gm+ bacilli non-spore forming Mobiluncus spp. GI tract, AB exotoxin BoNT (BoTox) presentation (botulism) flaccid paralysis, C. perfringens can lead to gastroenteritis spoiled foods soft tissue infxns cellulitis poor prognosis when: suppurative myositis myonecrosis septicemia, tetanus muscle spasms muscle rigidity early symptoms trismus (lockjaw) drooling sweating irritability back spasms, Gm+ bacilli non-spore forming Actinomyces spp. gums, anaerobic bacteria types facultative anaerobes, C. perfringens secretes many digestive exotoxins tissue & cell degrading exoenzymes serotypes A to E, Bacteriodes resist pen G, AB exotoxin BoNT (BoTox) presentation (botulism) food poisoning, Prevotella resist pen G, anaerobic bacteria types obligate anaerobe, Gm+ bacilli spore forming Bacillus, AB exotoxin TeNT, tetanospasmin compare/ contrast A subunits essentially identical proteases inhbs NT exocytosis pathway (SNARE) by cleaving SNARE proteins B subunits tgt diff neuron types, AB exotoxin BoNT (BoTox) action prevents release of ACh, tetanus muscle spasms muscle rigidity treatment debridement metronidazole antiTx globulin imm w tet toxoid pen. contraindicated inhibits GABA lt nerve regeneratn