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This Concept Map, created with IHMC CmapTools, has information related to: Mets Brain Tumors efficacy endpoints v6, Target lesion evaluated by Quantitative assessment, Time To Salvage Therapy In the Brain measured by Date of Salvage Therapy, MRI has types - With contrast - Without contrast - FLAIR, Organ specific lesion ID includes - Supratentorial: hemispheric (L, R) - Infratentorial: brain stem cerebellum, Progression free survival (PFS) has subtypes Non-CNS Lesion, Sum of the product of all lesions includes Total area of each leasion, Non-target lesion evaluated by Qualitative Assessment, Tumor Response is assessed with CT, Regional includes Convection enhanced delivery, METASTATIC BRAIN TUMORS EFFICACY ENDPOINTS include Overall Survival (OS), New lesion identified by Anatomical region, CNS (Brain) Lesion classified as NON-ENHANCING, Objective Response Rate (ORR) derived from Tumor Response, Repeated concepts/instances throughout the CMAP are denoted by dotted outline, Regional includes Surgical Resection, Non-CNS Lesion assesses by RECIST 1.1, Tumor Volume has attribute cm^3, Disease characteristics include Brain Tumor/Metastases Origin, Therapeutic Efficacy Endpoint is intersection of Therapeutic Intervention, ENHANCING classified as Non-measurable lesions