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This Concept Map, created with IHMC CmapTools, has information related to: STI.cmap, urethritis dysuria mucopurulent discharge from urethra urethral itching complications urethral constriction prostatitis epididymitis, T.vaginalis anaerobic, unicellular, flagellated, parasitic protozoan infects squamous epithelial cells including vaginal and urethral tissue Skene and Bartholin glands epididymis, Chlamydia trachomatis gram-negative intracellular bacterium -requires host cell symptoms infection of urethra and cervix invade epididymides, fallopian tubes, hepatic capsule clear discharge asymptomatic in women (75%), squamous epithelial cells including vaginal and urethral tissue Skene and Bartholin glands epididymis symptoms Male usually self-limiting, asymptomatic zinc in prostate has antibacterial effect urethra cleared during ejaculation, Neisseria gonorrhoeae treatment Cephalosporins (ceftriaxone) Gonococcal urethritis may resolve spontaneously in weeks, Parasitic Infections Trichomoniasis, Sexually Transmitted Infections caused by Viral Infections, infection of urethra and cervix invade epididymides, fallopian tubes, hepatic capsule clear discharge asymptomatic in women (75%) presentation epididymitis -fever, unilaterally painful, swollen scrotum Reiter syndrome - urethritis, conjunctivitis, arthritis, mucocutaneous lesions Acute urethral syndrome -dysuria, urinary frequency, sterile pus in urine cervicitis -yellow mucopurulent discharge from cervix, hypertrophic, edematous, friable area of cervix, 120 different types Papovaviridae family nonenveloped, circular, double-stranded DNA virus type 16 & 18 -high risk for cervical dysplasia type 6 & 11 - genital warts treatment cosmetic treatment of warts cryosurgery, podofilox, imiquimod, podophyllin resin, trichloroacetic acid, bichloroacetic acid, interferon, surgery, virus infects basal cell epithelium viral propagation cells undergo transformation, proliferate growth of warts symptoms condylomata acuminata- soft, skin coloured, whitish-pink to reddish-brown growths usually not painful, may cause dyspareunia friable, may bleed, Neisseria gonorrhoeae symptoms Male, Sexually Transmitted Infections caused by Bacterial Infections, Viral Infections Genital Herpes, silent infection serologic tests positive no clinical signs Stage 4, tertiary syphilis non-infectious disease gummas -destructive lesions of CNS, blood vessels, bones, skin severe hypersensitivity reaction CVS - aneurysms, heart valve insufficiencies, heart failure CNS - neurosyphilis, Chlamydia trachomatis gram-negative intracellular bacterium -requires host cell treatment azithromycin, doxycycline, Trichomoniasis treatment flagyl, entry of virus via mucocutaneous site or abraded skin viral replication in dermis and epidermis causes vesicle formation spreads via sensory nerves latent phase (oral-trigeminal ganglion, genital-dorsal sacral nerve root) reactivation- virus travels peripheral sensory nerves to dermal surface systemic symptoms fever, malaise, myalgias, lymphadenopathy, urinary retention, pharyngitis, aseptic meningitis, hepatitis, HSV-1 HSV-2 diagnosis viral tissue cultures identify HSV fluorescent antibody, neutralization, or serologic tests determine HSV-1 or HSV-2, Chlamydia trachomatis gram-negative intracellular bacterium -requires host cell chronic infection lymphogranuloma venereum - skin lesion spread to genital and rectal lymphatic tissue inflammation, necrosis, buboes, abscess of inguinal lymph nodes systemic infection (meningitis, pneumonitis), asymptomatic in 50% dysuria vaginal discharge abnormal menses dyspareunia cervical friability, erythema, purulent or mucopurulent discharge complications PID salpingitis bartholinitis sterility