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This Concept Map, created with IHMC CmapTools, has information related to: Pamela Chase, hypercortisolism has metabolic effects, GLUT 4 in muscle, Gluconeogenesis thus contributing to hyperglycemia, proteolysis results in wasting of muscle, Pamela Chase 35 year old female presents with violaceous abdominal striae, Pamela Chase 35 year old female given diagnostic tests including serum ACTH, metabolic effects inhibition of GLUT 4, Cushing syndrome (ACTH dependent) due to pituitary adenoma, Pamela Chase 35 year old female presents with dorsocervical fat pad (buffalo hump), Pamela Chase 35 year old female presents with moon facies, muscle manifests as atrophy of proximal muscle, muscle results in insulin resistance, high serum cortisol shows failure to suppress ACTH, neutrophilia supports CBC, androgen leads to hirsutism, adrenal gland specifically adrenal cortex, cortisol which results in hypercortisolism, metabolic effects stimulates fat deposition centrally, thin skin reveals underlying blood vessels, Pamela Chase 35 year old female presents with thin skin