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This Concept Map, created with IHMC CmapTools, has information related to: Frank Teller, Hashimoto's Thyroiditis confirmed by Low Free T4 Serum levels, proteins in epithelium cells less Growth and differentiation, Frank Teller does not have Secondary Hypothyroidism, Decreases Ca2+ levels in cardic myocytes, TRE lead to decreased transcription of proteins in epithelium cells, Frank Teller presents with Hyporeflexia, TSH stimulates release of T4, Antigen presenting cells (APCs) express MHC Class II, T4 unable to reach Peripheral Tissue, Primary Hypothyroidism possibly Hashimoto's Thyroiditis, autoimmune response due to loss of immune tolerance, Growth and differentiation results in Brittle nails, Th1 Cells secrete Interferon-gamma, proteins such as Sodium/Potassium pump, Uncoupling protein in Mitochondria leads to decreased heat, Fas (CD95) which is on Thyroid follicular cells, IgG-1 manifests as Anti-thyroglobulin (anti-Tg), Hashimoto's Thyroiditis confirmed by High TSH serum levels, cardiac contractility lead to Bradycardia, T3 typically inhibits formation of Na+/Ca2+ antiporter