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This Concept Map, created with IHMC CmapTools, has information related to: georgeShelton, Joint Receptors loss of function leads to Decreased proprioception, Upper Regions of the brain perceives pain, pacinian corpuscles respond to fast vibrations, George Shelton diagnosed with Diabetic distal polyneuropathy, loss of peripheral sensation leads to parasthesias (tingling), George Shelton presents with pain, Joint Receptors assocatied with A-beta fibers, Trebenifin used to treat Onychomycosis (tinea unguium), Dead Nerve cells leads to Decreased pain sensation, Hyperlipidemia contribute to Hardening/Thickening of Veins and Arteries, Dorsal horn ascends spinal cord, Reduced blood flow in Endoneurial vessels which leads to Dead Nerve cells, pacinian corpuscles respond to deep pressure, ectopic/spontaneous firing leads to stabbing pain, large fibers send signal to dorsal root ganglion, Diet high in Carbohydrates, Cholesterol and Saturated Fats contributes to Type II Diabetes Mellitus, Meissner's corpuscles Loss of function leads to Decreased vibratory sensation, loss of peripheral sensation due to Dead Nerve cells, ectopic/spontaneous firing leads to burning pain, upregulation of TRPV1 contribute to hyperexcitability