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This Concept Map, created with IHMC CmapTools, has information related to: Chris Turtle, obesity increases risk of gout, HGPRT defect could lead to gout, diagnostic studies indicates elevated creatinine levels, high cholesterol increases risk of gout, GMP together are inhibitors of purine synthesis, diagnostic studies includes negative xray of right elbow, Social history contains Poor diet, HGPRT into GMP, alcohol use contributes to high in purines, AMP together are inhibitors of purine synthesis, diuretic also contributes to hyperuricemia, high in purines includes adenine, Hydrochlorothiazide acts as a diuretic, apoptosis causing release of DNA, hyperuricemia identified through elevated serum uric acid, Chris Turtle has a family history, nociceptors perceived as pain in swollen, painful red joint, renal clearance if decreased hyperuricemia, Chris Turtle with a relevant Social history, dehydration contributes to hyperuricemia