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This Concept Map, created with IHMC CmapTools, has information related to: Physical Barriers, Psoriasin produced by skin has potent antimicrobial activity against E. Coli Thus We are resistant to colonization despite constant exposure., Antibacterial/antiviral substances Include linings of Urogenital tracts, Physical Barriers First line of defense against invading organisms, consists of Mucous Membranes, a viscuous fluid that entraps microbes May also contain Antibacterial/antiviral substances, Peptides and proteins with antimicrobial activity Example Psoriasin produced by skin has potent antimicrobial activity against E. Coli, Skin Two layers Mount active biochemical defense, Peptides and proteins with antimicrobial activity important because breaks in the skin/epithelia from scratches, wounds, insect bites, or abrasion provides easy access for microbes., Skin Two layers provide a kind of living "saran wrap", Antibacterial/antiviral substances Include linings of Gastrointestinal tract, Antibacterial/antiviral substances Include linings of respiratory tract, Mount active biochemical defense by synthesizing and deploying Peptides and proteins with antimicrobial activity, Antibacterial/antiviral substances Include linings of Eyes, Mucous Membranes Secrete mucous a viscuous fluid that entraps microbes, Physical Barriers First line of defense against invading organisms, consists of Skin