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This Concept Map, created with IHMC CmapTools, has information related to: Marfan Syndrome, Cardiovascular system mutation causes Aortic dilatation, Several body tissues including Ocular system, Pleiotropy with Multiple affected systems, Skeletal system mutaiton causes Scoliosis, Multiple affected systems including Ocular system, Several body tissues including Skeletal system, Marfan syndrome exhibits Pleiotropy, Multiple affected systems including Cardiovascular system, Scoliosis which is Curvature of spine, Skeletal system mutaiton causes Pectus Carinatum, Cardiovascular system mutation causes Mitral Valve Prolapse, Autosomal dominant mutation because Abnormal fibrillin bind and degrade normal fibrillin, Skeletal system mutaiton causes Arachnodactyly, Fibrillin found in Connective tissue, FBN1 encode Fibrillin, Connective tissue found in Several body tissues, Marfan syndrome inherited as Autosomal dominant mutation, Dolichostenomelia which is Long, slender lombs, Aortic dilatation which is Primary cause of mortality, FBN1 can have Mutations