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This Concept Map, created with IHMC CmapTools, has information related to: Huntington's Disease, Variable numbers of repetition including 27-35, Toxic protein aggregation blocks axonal transport, Variable numbers of repetition including >=40, <=26 which is Normal Unaffected, Huntington's Disease shows Variable Age of Onset, axonal transport leads to Early neuronal death, CAG repeat in Gene coding Huntingtin, CAG repeat shows Variable numbers of repetition, 27-35 which is Intermediate Unaffected, Huntington's Disease caused by Short Tandem Repeat Polymorphisms, >=40 which is Full penetrance Affected, Early neuronal death presents as Psychosis, Ubiquitin tagging causes proteolysis, Gene coding Huntingtin required for neurotrophic factor production, neurotrophic factor production mutation gives expanded glutamine residues, Variable Age of Onset determined by Variable numbers of repetition, Short Tandem Repeat Polymorphisms of CAG repeat, expanded glutamine residues causes Ubiquitin tagging, Early neuronal death presents as Chorea, Variable numbers of repetition including 30-39