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This Concept Map, created with IHMC CmapTools, has information related to: Antibiotics anti-protein synth, Tetracyclines broad, bacstatic, revers. 30s G-, G+ rst - ↓uptake, Δsite, expulsion, mod, Antibiotics Ribosome Binding ∅ Protein Synth Tetracyclines, Aminoglycosides 30s perm inhib Streptomycin, neomycin, kenamycin, tobramycin amikacin netilmicin, Antibiotics Ribosome Binding ∅ Protein Synth Oxazolidnones, Antibiotics Ribosome Binding ∅ Protein Synth Macrolides, Oxazolidnones N-spec, ∅ 50s subunit, ∅ cross-resist Rx - Linezolid - staph, strept., entero resvrd4 MRSA enteroc., Antibiotics Ribosome Binding ∅ Protein Synth Aminoglycosides, Tetracyclines broad, bacstatic, revers. 30s Rx- Chlamydia, Mycoplasma, Ricketsia, Lincosamide 50s Rx- Clindamycin - staph, anaerobic G- bacili (Clostridium), Streptogramins combo (A&B) Rx - Quinupristin-Dalfopristin (Synerced) - staph, strept, E. Faecium - only for vanco-rest. E. Faecium, Aminoglycosides 30s perm inhib G- (pseudomas), som G+ rst- strept & entero ∴ coadmin w/∅cell wall Rx- Amikacin- aminog. rst G- Streptomycin- TB, strept., enteroc. Enteroc. G+ only w/ cellwall combo, Chloramphenicol b-spec 50s reversible toxic to bone marrow Rx - Typhoid Fever, Antibiotics Ribosome Binding ∅ Protein Synth Streptogramins, Antibiotics Ribosome Binding ∅ Protein Synth Chloramphenicol, Macrolides b-spec, lactone ring bstatic, 23s of 50s Rx - erythromycin - G+ w/ Penicillin Allergy Pulmonary inf. Mycoplasma, Legionella, Chlamydia, Cmpylobacer rest - methylation 23s, Aminoglycosides 30s perm inhib rst - ↓uptake, Δsite, expulsion, mod, Antibiotics Ribosome Binding ∅ Protein Synth Lincosamide