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This Concept Map, created with IHMC CmapTools, has information related to: Bacteriology 10 intracellular bacteria intro mb26, intracellular bacteria char pathology is a result of, Chlamydia trachomatis disease eye, resp, and UTI infxns no build up of resistnce w: cervitis, salpingitis, PID, ...infertility m: nongonococcal urethritis, epididymitis, prostatis, proctitis lymphogranuloma venerum conjunctivitis -chronic (trachoma)...blndnss -adult inclusion -neonatal (mucopurulent) Reiter's syndrome: AB's against pathogen react w/ self Ag's infant pneumonia, Orientia species O. Tsutsugamushi scrub Typhus, tick, Chlamydophila pneumoniae dz pneumonia, Chlamydia trachomatis Tx azithromycin or doxycycline, Rickettsiaceae Genus Rickettsia, Mycoplasma reservoir transmission GI,resp tract droplts sexual, Anaplasmataceae tick- borne Ehrlichia caffeensis human monocytic ehrlichiosis, eye, resp, and UTI infxns no build up of resistnce w: cervitis, salpingitis, PID, ...infertility m: nongonococcal urethritis, epididymitis, prostatis, proctitis lymphogranuloma venerum conjunctivitis -chronic (trachoma)...blndnss -adult inclusion -neonatal (mucopurulent) Reiter's syndrome: AB's against pathogen react w/ self Ag's infant pneumonia e.g. urethritis symptoms 1-3wk incubtn discharge, dysuria pyuria 12wk resolves 25% asymptomatic, Mycoplasma pneumoniae diseases caused GU tract infxns, Rickettsia species R. typhi endemic Typhus exists constly in pop flea, Mycoplasma pneumoniae epidemiology world-wide, non-seasonal most cmn cause of pneumn in young adults on 10% inftd get pneumn, Mycoplasma pneumoniae char structure terminal attachmnt, IFN-gamma controls growth cycle EB ingested, 0hr reorgd into RB inside phgsm (vs. Rickttsia outside phgsm) fission within phagosome reorgd to RB to EB site of RB+EB/rep= inclsn bodies inclsn bodies released, ~48hr by extrusion/ exocytosis or by lysis via protease&Ca EB = extracllr, inert, spore-like RB = intrcllr, active, fission-> EB, Mycoplasma pneumoniae diseases caused "atypical" pneumonia, Mycoplasma pneumoniae char strictly aerobic, intracellular bacteria obligate, Mycoplasma pneumoniae virulence factors adhesin P1 binds/destroys cilia in ciliated epi, Mycoplasma pneumoniae char v. diff to culture, Rickettsia species R. rickettsii Rocky mtn spottd fever tick