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This Concept Map, created with IHMC CmapTools, has information related to: Bacteriology 5 G+ bacilli aerobes bacillus, Bacillus cereus illnesses eye infxn usu w/ trauma endocarditis meningitis osteomyelitis pneumonia, inhalation anthrax treatment early IV Ab hist. Pen curr pref: ciprofloxacin doxycycline cheaper 2nd/3rd gen not/necess, binary toxins (PA | EF or LF) cause seeding of organ systems, because it's an aerobic bacteria O2 doesn't induce sporulation Bacillus anthracis, virulence type consequence of lifecycle: sporulation only two of medical sporulating bacteria of medical importance, Bacillus anthracis pathogenesis spores enter macrophages ingest spores spores survive macrophages transport spores to lymph nodes spores germinate spores produce toxin, inhalation anthrax descrp spores enter lungs migrate to lymph multiple produce toxins toxins cause bleeding organ destruction, Bacillus cereus descrp central spore found in soil, rice and grains motile, binary toxins (PA | EF or LF) 2 types of A components lethal factor, binary toxins (PA | EF or LF) 2 types of A components edema factor, Bacillus cereus resistant to pen., Bacillus spp species Bacillus anthracis, emetic caused by pre-formed toxin pre-formed toxin, consequence of lifecycle: sporulation only two of medical sporulating bacteria of medical importance e.g. anaerobic Clostridium spp., none, monitor pt. AB therapy doesn't alter symptoms because pre-formed toxin, consequence of lifecycle: sporulation only two of medical sporulating bacteria of medical importance e.g. aerobic/ fac. anaerobic Bacillus spp, inhalation anthrax descrp use Std Precautions not spread by secrt, cutaneous anthrax descrp spore enters skin e.g. sheep papule -> vesicle -> eschar (black wound) mortality 5-20% if untreated, diarrheal treatment if progressed to systemactic, AB vancomycin clinda-, binary toxins (PA | EF or LF) B component protective antigen