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This Concept Map, created with IHMC CmapTools, has information related to: clostridium 2, cytopathic effects such as cell rounding with occasional stringing of cytoplasmic processes and granularity of degenerated cells, C. Difficile has a substance that inhibits bowel motility, C. Botulinum produces BoNT A-G, C. Perfringens produces theta toxin, toxin B produces cytopathic effects, hyaluronidase ???? break down tissue, collagenases will destroy the cell membrane, C. tetani produces tetanospasmin, toxin A will produce a positive fluid response, C. Perfringens produces alpha toxin, toxins that affect the cell membrane, alpha toxin that is active against membranes of muscle cells, WBCs, and platelets, BoNT A-G of which types C1 & C2 cause vascular permeability and have enterotoxic activity, C. Difficile produces toxin A, clostridium spp. produces toxins, tetanospasmin that rapidly binds to neural tissue, active against membranes of muscle cells, WBCs, and platelets and its necrotizing activity leads to the death of a variety of hosts cells and tissues, theta toxin which will affect the cell membrane, C. Difficile produces toxin B