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DNA replication, DNA Replication sometimes results in mutations, enzymes and proteins such as helix-destabilizing proteins, DNA helicase unzips DNA helix, an RNA primer which is replaced by DNA polymerase, mutations can be frameshift mutation, RNA primase creates an RNA primer, leading strand is synthesized continuously, semiconservative meaning one strand is conserved, DNA polymerase adds nucleotides, enzymes and proteins such as topoisomerases