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This Concept Map, created with IHMC CmapTools, has information related to: clostridium concept map, C. Difficile has a substance that inhibits bowel motility, cytopathic effects such as cell rounding with occasional stringing of cytoplasmic processes and granularity of degenerated cells, C. Perfringens produces theta toxin, C. Botulinum produces BoNT A-G, collagenases will destroy the cell membrane, hyaluronidase ???? break down tissue, toxin B produces cytopathic effects, C. tetani produces tetanospasmin, toxin A will produce a positive fluid response, toxins that affect the cell membrane, C. Perfringens produces alpha toxin, alpha toxin that is active against membranes of muscle cells, WBCs, and platelets, BoNT A-G of which types C1 & C2 cause vascular permeability and have enterotoxic activity, clostridium spp. produces toxins, C. Difficile produces toxin A, tetanospasmin that rapidly binds to neural tissue, active against membranes of muscle cells, WBCs, and platelets and its necrotizing activity leads to the death of a variety of hosts cells and tissues, C. Difficile produces toxin B, theta toxin which will affect the cell membrane