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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 15 Merged Map, tumor-specific transplantation antigens (TSTAs) may confer cross-immunity, inflammatory response as facilitated by tumor-associated macrophages (TAMs), Immune System (15.1) lead to Immunosurveillance theory (Section 15.7), immune system with cells such as macrophages, MHC class 1 molecules may attract cytotoxic T cells, Cytotoxic T cells can cause sutoimmune diseases, normal oligopeptides result in tolerance, holes in memebrane allow entrance of granzymes, allograft rejection truly due to cells being from different species, tolerance as oppose to self reactive lmphocytes, innate immune response is the sole respone in 99% of animal species, helper T cells release cytokines, Regulatory T cells express FOXP3 transcription factor, helper T cells activate B cells, antigen-presenting cells (APCs) uses proteins synthesized in the cells, proteins synthesized in the cells are routinely diverted and turned into oligopeptides, innate immune response uses natural killer (NK) cells, Antibody molecules recognize and bind Antigens, immunoevasion by suppressing tumor antigens, innate immune response uses immunocytes