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This Concept Map, created with IHMC CmapTools, has information related to: Chapter 8 terms, cell makes decisions about growth and quiescence, Myc oncoprotien perturbs the decision to phophorylatre pRb, Viral oncoproteins reveal how pRB blocks, Cell Cycle advance is irreversible, pRb function is closely linked to the contrls of differentiation, Cyclin-CDK complexes regulated by CDK inhibitors, Contolf of pRb function isperturbed in many cancers, core components of cell cycle clock include cyclin-dependent kinases, core components of cell cycle clock include cyclins, decisions about growth and quiescence during a specific period in the G1 phase, viral E1A seekout cellular targets, external signals influence cell's decision to enter into the active cell cycle, restrication point aka R point, Id transcription factors inhibit differentiation, pRB impliments growth VS. quiescence decisions, Dtype cyclins have other jobs, cell cycle clock deploys pRB, loss of checkpont controls has consequences, growth VS. quiescence decisions due to E2F transcription factors, embryonic stem cells show highly autonomous behavior