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This Concept Map, created with IHMC CmapTools, has information related to: 26Feb07IK_HW3_ECM_Concept_Map, heparan sulfates are composed of core protein, external signals trigger degradation of proteins, negative charge due to the presence of hydroxyl groups, laminin is an example of glycoproteins, hyaluronans do not have a core protein, external signals trigger degradation of mRNA, three polypeptides which feature repating Gly-X-Y, cell migration along the basement membrane, glycosaminoglycans posess a negative charge, extracellular matrix interacts with the cytoskeleton, cell proliferation requires replication of organelles, mRNA is transported through nuclear pores, binding receptors such as fibronectin, nucleus contains the DNA (genetic material), cells synthesize proteins, discrete ECM structures such as basement membrane, collagen iv functions as a barrier, negative charge due to the presence of sulfate groups, extracellular matrix is organized by cells, connective tissue is built from proteoglycans