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This Concept Map, created with IHMC CmapTools, has information related to: EDC&I cancer map, mutation leads to a loss of normal apoptosis, mitosis is dependent on normal activity of tumor suppressor gene, tumor suppressor gene loss of leads to uncontrolled division, CANCER causes loss of heterozygosity, environment such as carcinogen, CANCER causes oxidative damage, CANCER causes environment, mutation leads to a loss of normal replication fidelity, tumor suppressor gene examples of Retino-blastoma, radiation exploits uncontrolled division, mitosis is dependent on normal activity of oncogene, oxidative damage is prevented by antioxidant, mutation in DNA repair, diagnosed using array technology, carcinogen leads to mutation, oxidative damage leads to mutation, tumor can be malignant, diagnosed upon finding tumor, mutation leads to a loss of normal cell differentiation, mitosis loss of leads to uncontrolled division