WARNING:
JavaScript is turned OFF. None of the links on this concept map will
work until it is reactivated.
If you need help turning JavaScript On, click here.
This Concept Map, created with IHMC CmapTools, has information related to: LDL receptor def, Family History which includes premature coronary artery disease, TG hydrolization resulting in formation of IDL, thrombus clots a coronary artery, HMG CoA reductase which is activated by phosphoprotein phosphatase, cholesterol levels (300-400mg/dL) suggests parents with heterzygous FH genotype, bruits present in 10 year old girl, LDL via oxidative metabolites, becomes oxidized LDL, free intracellular cholesterol (FIC) esterfied for storage by ACAT, TG hydrolization creating free fatty acids, premature coronary artery disease suggests parents with heterzygous FH genotype, > 2% function LDL receptors suggests receptor negative condition, LDL receptor gene codes for LDL receptor, Atherosclerotic plaque may ulcerate and cause formation of thrombus, HDL donates ApoC-II, functional allele suggests autosomal codominant, endogenous lipids in the liver is secreted into plasma, 10 year old girl is found to have normal triglyceride levels, phosphoprotein phosphatase to synthesize de novo free cholesterol, free intracellular cholesterol (FIC) is converted to bile, receptor negative condition which is classifies as class 1 or class 2A mutation