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This Concept Map, created with IHMC CmapTools, has information related to: Kyle Hohimer And Luke Baker, a lack of an enzyme called Acid alpha-glucosidase, Age 1 Remeber Most die before the age of 1, Pompe's Disease is caused by a lack of an enzyme, Pompe's Disease ways to know or Symptoms, Inheriting it from both parents. By the mutated gene Acid alpha-glucosidase, Muscle weakness difficulty breathing the extremities differ from person to person but Most die before the age of 1, Symptoms including Muscle weakness difficulty breathing, glycogen with the buildup of this substance causes Muscle weakness difficulty breathing, Symptoms including Enlarged Heart, Pompe's Disease the way it spreads is by Inheriting it from both parents., lysosomes will double in size due to a lack of an enzyme, lysosomes produce Acid alpha-glucosidase, glycogen with This substance is a sugar used to store energy Within the muscle, Pompe's Disease originates at Age 1, Pompe's Disease is a Glycogen Stroage Disease (GSD), Acid alpha-glucosidase The lack of this enzyme allows a build up of. glycogen with